Compound Detail
CHEMBL383083
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL383083 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BDJWYLZYTHRBQR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
318.5
MW (Da)
2.65
ALogP
6
HBA
2
HBD
84.0
PSA (Ų)
0.52
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.65
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Complement C1s subcomponent CHEMBL3913 | Ki | 5.65 | 5.65 | 2240.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Complement C1s subcomponent | Ki | = | 2240.0 | nM | 5.65 | Inhibition of C1S | 16460935 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16460935 | 10.1016/j.bmcl.2006.01.036 | Complement C1s subcomponent | 1 |
Data from ChEMBL 36 via Core Engine