Compound Detail
CHEMBL385026
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL385026 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WVZMDIKZVKSPKS-LJQANCHMSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
410.5
MW (Da)
5.08
ALogP
5
HBA
0
HBD
61.2
PSA (Ų)
0.31
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Xenopus sp. CHEMBL612667 | EC50 | 6.66 | 6.66 | 220.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Xenopus sp. | EC50 | = | 220.0 | nM | 6.66 | Anesthetic activity in Xenopus tadpole measured as loss of righting reflex | 16884293 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16884293 | 10.1021/jm051207b | GABA-A receptor; anion channel | 1 |
| 16884293 | 10.1021/jm051207b | GABA-A receptor; alpha-1/beta-2/gamma-2 | 1 |
| 16884293 | 10.1021/jm051207b | Xenopus sp. | 1 |
| 16884293 | 10.1021/jm051207b | Serotonin 3 (5-HT3) receptor | 1 |
Data from ChEMBL 36 via Core Engine