Compound Detail
CHEMBL385168
AMINOFENTANYL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL385168 |
| Name | AMINOFENTANYL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WBHIZNRNVFOZMJ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
351.5
MW (Da)
3.08
ALogP
3
HBA
1
HBD
49.6
PSA (Ų)
0.83
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mu-type opioid receptor CHEMBL270 | IC50 | 5.68 | 5.68 | 2080.0 | 1 |
| Delta-type opioid receptor CHEMBL236 | IC50 | 4.89 | 4.89 | 13000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mu-type opioid receptor | IC50 | = | 2080.0 | nM | 5.68 | Displacement of [3H]DAMGO from rat mu opioid receptor | 16828552 |
| Delta-type opioid receptor | IC50 | = | 13000.0 | nM | 4.89 | Displacement of [3H]DPDPE from human delta opioid receptor | 16828552 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16828552 | 10.1016/j.bmcl.2006.06.040 | Mu-type opioid receptor | 2 |
| 16828552 | 10.1016/j.bmcl.2006.06.040 | Delta-type opioid receptor | 2 |
Data from ChEMBL 36 via Core Engine