Compound Detail
CHEMBL3885493
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3885493 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FOLMXBPXGPARDX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
364.8
MW (Da)
4.46
ALogP
5
HBA
0
HBD
52.3
PSA (Ų)
0.52
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 2 CHEMBL5137 | EC50 | 6.64 | 6.64 | 230.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 2 | EC50 | = | 230.0 | nM | 6.64 | Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells... | 27914948 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27914948 | 10.1016/j.bmc.2016.11.018 | ADMET | 5 |
| 27914948 | 10.1016/j.bmc.2016.11.018 | Metabotropic glutamate receptor 2 | 2 |
Data from ChEMBL 36 via Core Engine