Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL3892224

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Clc1ccccc1/C=N/c1nc(-c2ccccc2)cs1

Basic Information

ChEMBL ID CHEMBL3892224
Phase Preclinical
Structure Type MOL
InChI Key XNBWNUVNJMDFSP-VCHYOVAHSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

298.8
MW (Da)
5.21
ALogP
3
HBA
0
HBD
25.2
PSA (Ų)
0.61
QED
1
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C16H11ClN2S
MW 298.80
Aromatic Rings 3
Heavy Atoms 20
NP-Likeness -1.85

Activity Summary

IC50 1 meas. best 4.88

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Urease
CHEMBL4161
IC50 4.88 4.88 13030.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Urease IC50 = 13030.0 nM 4.88 Inhibition Assay: Reaction mixtures consisting of 25 μL (1 unit/well) of Jack be... -

Data from ChEMBL 36 via Core Engine