Compound Detail
CHEMBL389673
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Basic Information
| ChEMBL ID | CHEMBL389673 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GMOPXWDCZJACIN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
321.8
MW (Da)
3.77
ALogP
3
HBA
2
HBD
66.4
PSA (Ų)
0.82
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.36
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | IC50 | 5.36 | 5.36 | 4400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | IC50 | = | 4400.0 | nM | 5.36 | Inhibition of HCV 1b BK NS5B delta21 RNA polymerase expressed in Escherichia col... | 17402724 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17402724 | 10.1021/jm061428x | Hepatitis C virus | 1 |
Data from ChEMBL 36 via Core Engine