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Compound Detail

CHEMBL3903905

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C[C@@H](Cc1cccc(N)c1)NC[C@@H](O)c1cc(O)cc(O)c1

Basic Information

ChEMBL ID CHEMBL3903905
Phase Preclinical
Structure Type MOL
InChI Key YSDUJIGQJOLYND-APPDUMDISA-N
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

302.4
MW (Da)
1.93
ALogP
5
HBA
5
HBD
98.7
PSA (Ų)
0.53
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C17H22N2O3
MW 302.37
Aromatic Rings 2
Heavy Atoms 22
NP-Likeness 0.18

Activity Summary

Kd 1 meas. best 4.54
Ki 1 meas. best 4.54

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Beta-2 adrenergic receptor
CHEMBL210
Kd 4.54 4.54 28840.0 1
Beta-2 adrenergic receptor
CHEMBL210
Ki 4.54 4.54 28749.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine