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Compound Detail

CHEMBL3911047

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O=C(Nc1cccnc1)N1CCN(Cc2ccc(Br)c(Br)c2)CC1

Basic Information

ChEMBL ID CHEMBL3911047
Phase Preclinical
Structure Type MOL
InChI Key DXQRYNSQNIOEKG-UHFFFAOYSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

454.2
MW (Da)
3.96
ALogP
3
HBA
1
HBD
48.5
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C17H18Br2N4O
MW 454.17
Aromatic Rings 2
Heavy Atoms 24
NP-Likeness -1.97

Activity Summary

IC50 2 meas. best 7.57

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Fatty-acid amide hydrolase 1
CHEMBL2243
IC50 7.57 7.57 27.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine