Compound Detail
CHEMBL3916262
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3916262 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DHGBHGKSBRNXGH-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
357.4
MW (Da)
3.07
ALogP
6
HBA
0
HBD
74.1
PSA (Ų)
0.72
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 5.52 | 5.495 | 3020.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 3020.0 | nM | 5.52 | Cytotoxicity against human HL60 cells assessed as decrease in cell viability aft... | - |
| NON-PROTEIN TARGET | IC50 | = | 3360.0 | nM | 5.47 | Cytotoxicity against human HCT116 cells assessed as decrease in cell viability a... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C6MD00216A | NON-PROTEIN TARGET | 7 |
Data from ChEMBL 36 via Core Engine