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Compound Detail

CHEMBL391772

PHELLIGRIDIN G
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O=C1C=C(/C=C/c2ccc(O)c(O)c2)OC12C(c1cc3oc(=O)c4cc(O)c(O)cc4c3c(=O)o1)=Cc1cc(O)c(O)cc12

Basic Information

ChEMBL ID CHEMBL391772
Name PHELLIGRIDIN G
Phase Preclinical
Structure Type MOL
InChI Key FNYDGJUOSXPBRL-HNQUOIGGSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

594.5
MW (Da)
4.08
ALogP
12
HBA
6
HBD
208.1
PSA (Ų)
0.13
QED
3
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C32H18O12
MW 594.48
Aromatic Rings 5
Heavy Atoms 44
NP-Likeness 1.43

Activity Summary

IC50 1 meas. best 4.04

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
IC50 4.04 4.04 92300.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
NON-PROTEIN TARGET IC50 = 92300.0 nM 4.04 Antioxidant activity assessed as superoxide radical scavenging activity by xanth... 17980585

Literature References

PubMed DOI Target Context # Activities
17980585 10.1016/j.bmcl.2007.10.072 Unchecked 2
17980585 10.1016/j.bmcl.2007.10.072 NON-PROTEIN TARGET 1

Data from ChEMBL 36 via Core Engine