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Compound Detail

CHEMBL3923099

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Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c1-c1nc(C2CC2)ns1

Basic Information

ChEMBL ID CHEMBL3923099
Phase Preclinical
Structure Type MOL
InChI Key MZJLCMWYWDNXAI-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

455.6
MW (Da)
5.47
ALogP
6
HBA
2
HBD
92.2
PSA (Ų)
0.60
QED
1
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C23H25N3O3S2
MW 455.61
Aromatic Rings 2
Heavy Atoms 31
NP-Likeness -0.84

Activity Summary

IC50 2 meas. best 7.89

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Fatty acid-binding protein, adipocyte
CHEMBL2083
IC50 7.89 7.89 13.0 1
Fatty acid-binding protein 5
CHEMBL3674
IC50 7.8 7.8 16.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine