Compound Detail
CHEMBL3930718
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3930718 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NQRVJJNFNBPWHN-FBBABVLZSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
360.5
MW (Da)
4.44
ALogP
3
HBA
2
HBD
74.6
PSA (Ų)
0.67
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 6.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prostaglandin E2 receptor EP2 subtype CHEMBL1881 | EC50 | 6.99 | 6.99 | 102.0 | 1 |
| Prostaglandin E2 receptor EP3 subtype CHEMBL3710 | EC50 | 5.47 | 5.47 | 3390.0 | 1 |
| Thromboxane A2 receptor CHEMBL2069 | EC50 | 5.37 | 5.37 | 4273.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prostaglandin E2 receptor EP2 subtype | EC50 | = | 102.0 | nM | 6.99 | Agonist activity at human recombinant EP2 receptor expressed in HEK293 cells ass... | - |
| Prostaglandin E2 receptor EP3 subtype | EC50 | = | 3390.0 | nM | 5.47 | Agonist activity at human recombinant EP3A receptor expressed in HEK293 cells as... | - |
| Thromboxane A2 receptor | EC50 | = | 4273.0 | nM | 5.37 | Agonist activity at human recombinant TP receptor expressed in HEK293 cells asse... | - |
Data from ChEMBL 36 via Core Engine