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Compound Detail

CHEMBL3930835

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CCCCC[C@H](C)NC[C@H](O)c1cc(O)cc(O)c1

Basic Information

ChEMBL ID CHEMBL3930835
Phase Preclinical
Structure Type MOL
InChI Key DFGXCGQPCWUBML-NHYWBVRUSA-N
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

267.4
MW (Da)
2.69
ALogP
4
HBA
4
HBD
72.7
PSA (Ų)
0.55
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H25NO3
MW 267.37
Aromatic Rings 1
Heavy Atoms 19
NP-Likeness 0.64

Activity Summary

Kd 1 meas. best 4.5
Ki 1 meas. best 4.5

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Beta-2 adrenergic receptor
CHEMBL210
Kd 4.5 4.5 31623.0 1
Beta-2 adrenergic receptor
CHEMBL210
Ki 4.5 4.5 31440.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine