Compound Detail
CHEMBL3937026
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Basic Information
| ChEMBL ID | CHEMBL3937026 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GFASAZHPYNPNGE-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
429.5
MW (Da)
4.35
ALogP
3
HBA
0
HBD
28.5
PSA (Ų)
0.60
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Endothelial lipase CHEMBL5080 | IC50 | 6.02 | 6.02 | 959.0 | 1 |
| Endothelial lipase CHEMBL2380190 | IC50 | 6.0 | 6.0 | 1001.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Endothelial lipase | IC50 | = | 959.0 | nM | 6.02 | Endothelial Lipase Assay: To assay for cell surface lipase activity, cells expre... | - |
| Endothelial lipase | IC50 | = | 1001.0 | nM | 6.0 | Endothelial Lipase Assay: To assay for cell surface lipase activity, cells expre... | - |
Data from ChEMBL 36 via Core Engine