Compound Detail
CHEMBL3940359
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Basic Information
| ChEMBL ID | CHEMBL3940359 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YXMYUZGNDIAWAU-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
419.9
MW (Da)
5.74
ALogP
3
HBA
1
HBD
49.8
PSA (Ų)
0.68
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.36
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 4 CHEMBL5339 | EC50 | 6.36 | 6.3 | 440.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 4 | EC50 | = | 440.0 | nM | 6.36 | Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed... | 28105274 |
| Free fatty acid receptor 4 | EC50 | = | 580.0 | nM | 6.24 | Agonist activity at ARMS2-PK2 -tagged human GPR120 short isoform expressed in CH... | 28105274 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28105274 | 10.1021/acsmedchemlett.6b00360 | Free fatty acid receptor 4 | 2 |
Data from ChEMBL 36 via Core Engine