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Compound Detail

CHEMBL3962195

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O=C(O)c1cccc(Nc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])c1

Basic Information

ChEMBL ID CHEMBL3962195
Phase Preclinical
Structure Type MOL
InChI Key IXLRLXCTHVMJJM-UHFFFAOYSA-N
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

303.2
MW (Da)
2.94
ALogP
6
HBA
2
HBD
135.6
PSA (Ų)
0.64
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C13H9N3O6
MW 303.23
Aromatic Rings 2
Heavy Atoms 22
NP-Likeness -1.40

Activity Summary

Ki 3 meas. best 6.42

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Aldo-keto reductase family 1 member C3
CHEMBL4681
Ki 6.42 6.42 380.0 1
Aldo-keto reductase family 1 member C2
CHEMBL5847
Ki 5.88 5.88 1320.0 1
Aldo-keto reductase family 1 member C1
CHEMBL5905
Ki 5.58 5.58 2660.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine