Compound Detail
CHEMBL3967504
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Basic Information
| ChEMBL ID | CHEMBL3967504 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GTNYJWYYNOSATA-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
391.9
MW (Da)
5.40
ALogP
3
HBA
1
HBD
32.7
PSA (Ų)
0.75
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 6.48
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 4 CHEMBL5339 | EC50 | 6.48 | 6.06 | 330.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 4 | EC50 | = | 330.0 | nM | 6.48 | Agonist activity at ARMS2-PK2 -tagged human GPR120 short isoform expressed in CH... | 28105274 |
| Free fatty acid receptor 4 | EC50 | = | 472.0 | nM | 6.33 | FLIPR Assay: On the day before the measurement day, CHO cells expressing human G... | - |
| Free fatty acid receptor 4 | EC50 | = | 4300.0 | nM | 5.37 | Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed... | 28105274 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28105274 | 10.1021/acsmedchemlett.6b00360 | Free fatty acid receptor 4 | 2 |
Data from ChEMBL 36 via Core Engine