Compound Detail
CHEMBL3986063
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Basic Information
| ChEMBL ID | CHEMBL3986063 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UCJXYPHNWBXQJX-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
343.4
MW (Da)
5.78
ALogP
1
HBA
0
HBD
4.9
PSA (Ų)
0.57
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.44
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Endothelial lipase CHEMBL2380190 | IC50 | 7.44 | 7.44 | 36.0 | 1 |
| Endothelial lipase CHEMBL5080 | IC50 | 7.37 | 7.37 | 43.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Endothelial lipase | IC50 | = | 36.0 | nM | 7.44 | Endothelial Lipase Assay: To assay for cell surface lipase activity, cells expre... | - |
| Endothelial lipase | IC50 | = | 43.0 | nM | 7.37 | Endothelial Lipase Assay: To assay for cell surface lipase activity, cells expre... | - |
Data from ChEMBL 36 via Core Engine