Compound Detail
CHEMBL402475
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
C/C1=C\[C@@H](O)C/C(C)=C/[C@H](O)C[C@@](C)(O)/C=C/[C@H](C(C)C)CC1
Basic Information
| ChEMBL ID | CHEMBL402475 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZRUCLTHCKNSADG-LOXHLNSESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
322.5
MW (Da)
3.75
ALogP
3
HBA
3
HBD
60.7
PSA (Ų)
0.64
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.06
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hippocampus CHEMBL613631 | EC50 | 7.06 | 7.06 | 87.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hippocampus | EC50 | = | 87.0 | nM | 7.06 | Neuroprotective activity in Sprague-Dawley rat hippocampal slice assessed as rev... | 23769165 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23769165 | 10.1016/j.bmc.2013.05.018 | Hippocampus | 3 |
| 18222089 | 10.1016/j.bmc.2007.12.056 | NON-PROTEIN TARGET | 2 |
Data from ChEMBL 36 via Core Engine