Compound Detail
CHEMBL405031
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CCCCCCCCCCCCCCCC(=O)OCCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C)C(C)C
Basic Information
| ChEMBL ID | CHEMBL405031 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OFFBJGTUNGRSBT-QJFRHGNISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
1227.6
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 5.56
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Type-1 angiotensin II receptor CHEMBL3374 | Kd | 5.56 | 5.56 | 2754.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Type-1 angiotensin II receptor | Kd | = | 2754.23 | nM | 5.56 | Dissociation constant for [125 I] Ang binding to type 1 Angiotensin II receptor ... | 9379447 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9379447 | 10.1021/jm9608669 | Type-1 angiotensin II receptor | 3 |
| 9379447 | 10.1021/jm9608669 | Oryctolagus cuniculus | 1 |
Data from ChEMBL 36 via Core Engine