Compound Detail
CHEMBL405787
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Basic Information
| ChEMBL ID | CHEMBL405787 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RIVKDDXPCFBMOV-PZSVDHCGSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
306.5
MW (Da)
4.78
ALogP
2
HBA
2
HBD
40.5
PSA (Ų)
0.68
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hippocampus CHEMBL613631 | EC50 | 7.2 | 7.2 | 63.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hippocampus | EC50 | = | 63.0 | nM | 7.2 | Neuroprotective activity in Sprague-Dawley rat hippocampal slice assessed as rev... | 23769165 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18222089 | 10.1016/j.bmc.2007.12.056 | PC-3M | 6 |
| 18222089 | 10.1016/j.bmc.2007.12.056 | NON-PROTEIN TARGET | 6 |
| 23769165 | 10.1016/j.bmc.2013.05.018 | Hippocampus | 4 |
Data from ChEMBL 36 via Core Engine