Compound Detail
CHEMBL4070849
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Basic Information
| ChEMBL ID | CHEMBL4070849 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OYAZLIIROJSWCO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
340.4
MW (Da)
4.26
ALogP
3
HBA
1
HBD
56.0
PSA (Ų)
0.77
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| G-protein coupled receptor 52 CHEMBL3297639 | EC50 | 6.58 | 6.58 | 260.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| G-protein coupled receptor 52 | EC50 | = | 260.0 | nM | 6.58 | Agonist activity at human GPR52 expressed in CHO cells assessed as increase in c... | 28433511 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28433511 | 10.1016/j.bmc.2017.03.064 | G-protein coupled receptor 52 | 2 |
Data from ChEMBL 36 via Core Engine