Compound Detail
CHEMBL409627
CONFERTIFLORIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL409627 |
| Name | CONFERTIFLORIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VWBKXLDATRBPOE-VICSMPQUSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
306.4
MW (Da)
2.04
ALogP
5
HBA
0
HBD
69.7
PSA (Ų)
0.55
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prostaglandin G/H synthase 2 CHEMBL230 | IC50 | 5.54 | 5.54 | 2900.0 | 1 |
| Platelet CHEMBL4296519 | IC50 | 5.05 | 5.05 | 8880.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prostaglandin G/H synthase 2 | IC50 | = | 2900.0 | nM | 5.54 | Inhibition of COX2 | 16038536 |
| Platelet | IC50 | = | 8880.0 | nM | 5.05 | Inhibition of serotonin release in bovine platelets | 18271521 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18271521 | 10.1021/jm701318x | Platelet | 1 |
| 16038536 | 10.1021/np049655u | Prostaglandin G/H synthase 2 | 1 |
Data from ChEMBL 36 via Core Engine