Compound Detail
CHEMBL4106594
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4106594 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | POSMNGDKSNBSGR-SNVBAGLBSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
395.7
MW (Da)
1.38
ALogP
6
HBA
4
HBD
156.4
PSA (Ų)
0.43
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 CHEMBL2787 | EC50 | 5.21 | 5.21 | 6200.0 | 1 |
| Metabotropic glutamate receptor 8 CHEMBL2718 | EC50 | 4.42 | 4.42 | 38200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 | EC50 | = | 6200.0 | nM | 5.21 | Pharmacological Assay: Metabotropic glutamate receptors were transiently transfe... | - |
| Metabotropic glutamate receptor 8 | EC50 | = | 38200.0 | nM | 4.42 | Pharmacological Assay: Metabotropic glutamate receptors were transiently transfe... | - |
Data from ChEMBL 36 via Core Engine