Compound Detail
CHEMBL4114743
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Basic Information
| ChEMBL ID | CHEMBL4114743 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ISCCHVIRTOEBAV-KBKYJPHKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
405.4
MW (Da)
1.71
ALogP
8
HBA
1
HBD
114.1
PSA (Ų)
0.52
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | IC50 | 8.05 | 8.05 | 9.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | IC50 | = | 9.0 | nM | 8.05 | Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay: The kinase... | - |
Data from ChEMBL 36 via Core Engine