Compound Detail
CHEMBL41166
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Basic Information
| ChEMBL ID | CHEMBL41166 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RBCKGMDFAAHELJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
457.6
MW (Da)
2.96
ALogP
3
HBA
5
HBD
120.1
PSA (Ų)
0.17
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuropeptide Y receptor type 1 CHEMBL4777 | IC50 | 4.66 | 4.66 | 21800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuropeptide Y receptor type 1 | IC50 | = | 21800.0 | nM | 4.66 | NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine... | 10915060 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10915060 | 10.1016/s0960-894x(00)00292-4 | Neuropeptide Y receptor type 1 | 1 |
Data from ChEMBL 36 via Core Engine