Compound Detail
CHEMBL4168774
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Basic Information
| ChEMBL ID | CHEMBL4168774 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QUDMQNDHONHCJK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
432.5
MW (Da)
3.39
ALogP
7
HBA
1
HBD
88.4
PSA (Ų)
0.44
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | IC50 | 5.19 | 5.19 | 6510.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | IC50 | = | 6510.0 | nM | 5.19 | Inhibition of human GST-tagged c-MET using KKKSPGEYVNIEFG as substrate preincuba... | 29202410 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29202410 | 10.1016/j.ejmech.2017.11.073 | Hepatocyte growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine