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Compound Detail

CHEMBL4172192

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CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@@H](O)[C@H](Oc2c(-c3cc(O)c(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)O[C@H]1C

Basic Information

ChEMBL ID CHEMBL4172192
Phase Preclinical
Structure Type MOL
InChI Key HIVURPVQOPPNFN-HXJXXOFRSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

548.5
MW (Da)
1.34
ALogP
14
HBA
6
HBD
222.7
PSA (Ų)
0.20
QED
3
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C25H24O14
MW 548.45
Aromatic Rings 3
Heavy Atoms 39
NP-Likeness 2.07

Activity Summary

IC50 2 meas. best 5.47

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
No relevant target
CHEMBL2362975
IC50 5.47 5.47 3400.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
No relevant target IC50 = 3400.0 nM 5.47 Antioxidant activity assessed as DPPH radical scavenging activity measured after... 29300477

Literature References

PubMed DOI Target Context # Activities
29300477 10.1021/acs.jnatprod.7b00564 Tyrosinase 1
29300477 10.1021/acs.jnatprod.7b00564 No relevant target 1

Data from ChEMBL 36 via Core Engine