Compound Detail
CHEMBL4207261
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Basic Information
| ChEMBL ID | CHEMBL4207261 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HSZOZDPOYZAYTH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
366.4
MW (Da)
4.82
ALogP
5
HBA
0
HBD
57.9
PSA (Ų)
0.59
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| BV-2 CHEMBL614781 | IC50 | 4.43 | 4.43 | 36900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| BV-2 | IC50 | = | 36900.0 | nM | 4.43 | Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induc... | 29482940 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29482940 | 10.1016/j.bmcl.2018.02.026 | BV-2 | 2 |
Data from ChEMBL 36 via Core Engine