Compound Detail
CHEMBL421464
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Basic Information
| ChEMBL ID | CHEMBL421464 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LJTNASVPJCYYMC-YJBOKZPZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
382.4
MW (Da)
1.80
ALogP
5
HBA
2
HBD
101.6
PSA (Ų)
0.51
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.04
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Proteasome CHEMBL612443 | Ki | 5.04 | 5.04 | 9200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Proteasome | Ki | = | 9200.0 | nM | 5.04 | Inhibitory constant for the inactivation of the chymotrypsin like activity of pr... | 9871688 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9871688 | 10.1016/s0960-894x(98)00030-4 | Proteasome | 1 |
Data from ChEMBL 36 via Core Engine