Compound Detail
CHEMBL4215938
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Basic Information
| ChEMBL ID | CHEMBL4215938 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NWHJOAWWJLNVQU-ZZXKWVIFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
222.2
MW (Da)
0.32
ALogP
4
HBA
4
HBD
98.7
PSA (Ų)
0.34
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 6.05 | 6.05 | 900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 900.0 | nM | 6.05 | Antimalarial activity against Plasmodium falciparum infected in human erythrocyt... | 28241112 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28241112 | 10.1021/acs.jmedchem.6b01595 | Plasmodium falciparum | 1 |
Data from ChEMBL 36 via Core Engine