Compound Detail
CHEMBL424628
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL424628 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IRIJDMFYNHCYLC-UHNVWZDZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
316.2
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus 1 CHEMBL378 | EC50 | 4.54 | 4.54 | 28900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus 1 | EC50 | = | 28900.0 | nM | 4.54 | Antiviral activity against Immunodeficiency virus type-1 (HIV-1) in peripheral b... | 11052795 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11052795 | 10.1021/jm990113x | Human immunodeficiency virus 1 | 1 |
| 11052795 | 10.1021/jm990113x | Hepatitis B virus | 1 |
| 11052795 | 10.1021/jm990113x | ADMET | 1 |
| 11052795 | 10.1021/jm990113x | CCRF-CEM | 1 |
| 11052795 | 10.1021/jm990113x | Vero | 1 |
Data from ChEMBL 36 via Core Engine