Compound Detail
CHEMBL424787
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL424787 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QNFYWRWLVYZGOG-KRWDZBQOSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
395.4
MW (Da)
3.64
ALogP
5
HBA
3
HBD
99.1
PSA (Ų)
0.53
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 7.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL3072 | Ki | 7.19 | 7.19 | 64.6 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | Ki | = | 65.0 | nM | 7.19 | Binding Affinity towards Rat Androgen Receptor was determined using [3H]- mibole... | 10691684 |
| Androgen receptor | Ki | = | 64.57 | nM | 7.19 | Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventr... | 15715462 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10691684 | 10.1021/jm990027x | Androgen receptor | 1 |
| 15715462 | 10.1021/jm0495879 | Androgen receptor | 1 |
Data from ChEMBL 36 via Core Engine