Compound Detail
CHEMBL425529
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Basic Information
| ChEMBL ID | CHEMBL425529 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UHWFKVBMPMUNLY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
473.5
MW (Da)
3.51
ALogP
7
HBA
1
HBD
88.5
PSA (Ų)
0.46
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Gonadotropin-releasing hormone receptor CHEMBL1855 | Ki | 6.9 | 6.9 | 125.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Gonadotropin-releasing hormone receptor | Ki | = | 125.0 | nM | 6.9 | Binding affinity was determined against human gonadotropin-releasing hormone rec... | 15713397 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15713397 | 10.1016/j.bmcl.2005.01.009 | Gonadotropin-releasing hormone receptor | 1 |
Data from ChEMBL 36 via Core Engine