Compound Detail
CHEMBL426490
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Basic Information
| ChEMBL ID | CHEMBL426490 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FHVXFCIEMXSRJD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
590.4
MW (Da)
6.05
ALogP
7
HBA
2
HBD
101.8
PSA (Ų)
0.16
QED
2
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Complement C1s subcomponent CHEMBL3913 | Ki | 6.8 | 6.8 | 160.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Complement C1s subcomponent | Ki | = | 160.0 | nM | 6.8 | Inhibition of C1S | 16460935 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16460935 | 10.1016/j.bmcl.2006.01.036 | Complement C1s subcomponent | 1 |
Data from ChEMBL 36 via Core Engine