Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL427979

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
O=C(CCCCc1ccccc1)OC[C@H]1C[C@@H]2O[C@H]1[C@H]1C(=O)OC(=O)[C@H]12

Basic Information

ChEMBL ID CHEMBL427979
Phase Preclinical
Structure Type MOL
InChI Key WUGCRDYIDJRBHD-PSOLEGPJSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

358.4
MW (Da)
2.05
ALogP
6
HBA
0
HBD
78.9
PSA (Ų)
0.42
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H22O6
MW 358.39
Aromatic Rings 1
Heavy Atoms 26
NP-Likeness 0.90

Activity Summary

Ki 1 meas. best 5.64

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Ki 5.64 5.64 2300.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked Ki = 2300.0 nM 5.64 Inhibition of Protein phosphatase 2B -

Literature References

PubMed DOI Target Context # Activities
- 10.1016/S0960-894X(97)00141-8 Unchecked 1

Data from ChEMBL 36 via Core Engine