Compound Detail
CHEMBL4280830
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Basic Information
| ChEMBL ID | CHEMBL4280830 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CBSOPWMHWCBQLT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
341.4
MW (Da)
2.84
ALogP
5
HBA
1
HBD
72.5
PSA (Ų)
0.82
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.93
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma CHEMBL235 | IC50 | 4.93 | 4.93 | 11700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma | IC50 | = | 11700.0 | nM | 4.93 | Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-t... | 30429097 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30429097 | 10.1016/j.bmc.2018.10.033 | Mus musculus | 1 |
| 30429097 | 10.1016/j.bmc.2018.10.033 | Peroxisome proliferator-activated receptor gamma | 1 |
Data from ChEMBL 36 via Core Engine