Compound Detail
CHEMBL4284575
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4284575 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZFMPORMMFCGMPG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
307.4
MW (Da)
3.41
ALogP
5
HBA
1
HBD
70.3
PSA (Ų)
0.80
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.92 | 6.92 | 119.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 119.0 | nM | 6.92 | Inhibition of LPS-induced PGE2 production in C57BL6 mouse peritoneal cells measu... | 30006172 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30006172 | 10.1016/j.ejmech.2018.07.010 | Unchecked | 3 |
Data from ChEMBL 36 via Core Engine