Compound Detail
CHEMBL4290239
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4290239 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OLTJBWNNCOSOHB-WYMLVPIESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
219.3
MW (Da)
3.27
ALogP
3
HBA
2
HBD
52.8
PSA (Ų)
0.43
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Estrogen receptor beta CHEMBL242 | EC50 | 6.22 | 6.22 | 600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Estrogen receptor beta | EC50 | = | 600.0 | nM | 6.22 | Inhibition of fluorescein-tagged estrogen binding to GST-tagged ERbeta (unknown ... | 30144697 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30144697 | 10.1016/j.ejmech.2018.08.006 | Estrogen receptor | 3 |
| 30144697 | 10.1016/j.ejmech.2018.08.006 | Estrogen receptor beta | 3 |
| 30144697 | 10.1016/j.ejmech.2018.08.006 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine