Compound Detail
CHEMBL4291156
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4291156 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WGALBHNNJFJVCA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
465.6
MW (Da)
4.94
ALogP
6
HBA
1
HBD
87.0
PSA (Ų)
0.32
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.88
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 2 CHEMBL253 | Ki | 5.88 | 5.88 | 1307.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 2 | Ki | = | 1307.0 | nM | 5.88 | Displacement of [3H]CP55,940 from N-terminal HA-tagged human CB2 receptor expres... | 29407590 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29407590 | 10.1016/j.ejmech.2017.11.076 | Cannabinoid receptor 2 | 5 |
| 29407590 | 10.1016/j.ejmech.2017.11.076 | Cannabinoid receptor 1 | 5 |
| 29407590 | 10.1016/j.ejmech.2017.11.076 | HEK293 | 2 |
| 29407590 | 10.1016/j.ejmech.2017.11.076 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine