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Compound Detail

CHEMBL4297801

PEGUNIGALSIDASE ALFA
💊 Approved Drug
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💊 Approved Drug
No structure available
ChEMBL ↗

Basic Information

ChEMBL ID CHEMBL4297801
Name PEGUNIGALSIDASE ALFA
Phase Approved
Structure Type SEQ
Therapeutic ✓ Yes

Known Names

Elfabrio Pegunigalsidasa alfa Pegunigalsidase alfa Pegunigalsidase alfa-iwxj Prx-102
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
5
Known Names
1
Indications
1
Mechanisms

Drug Information

Molecule Type Enzyme
First Approval 2023
Availability Prescription
Chirality Single Enantiomer

Flags

Black Box Warning
USAN Stem -ase; peg-

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Globotriosylceramide hydrolytic enzyme HYDROLYTIC ENZYME Globotriosylceramide ✓ ✓

Indications

Fabry Disease

ATC Classification

A16AB20
pegunigalsidase alfa
Level 1: ALIMENTARY TRACT AND METABOLISM
Level 2: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS

Drug Warnings

Black Box Warning
immune system toxicity
Country: United States
Black Box Warning
neurotoxicity
Country: United States

Data from ChEMBL 36 via Core Engine