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Compound Detail

CHEMBL4297803

PEGZILARGINASE
💊 Approved Drug
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💊 Approved Drug
No structure available

Basic Information

ChEMBL ID CHEMBL4297803
Name PEGZILARGINASE
Phase Approved
Structure Type SEQ
Therapeutic ✓ Yes

Known Names

AEB-1102 Aeb1102 Co-argi-peg Loargys Pegzilarginasa Pegzilarginase
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
6
Known Names
6
Indications
1
Mechanisms

Drug Information

Molecule Type Enzyme
First Approval 2023
Availability Unknown
Chirality Single Enantiomer
USAN Stem -ase; peg-

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
L-arginine hydrolytic enzyme HYDROLYTIC ENZYME L-arginine

Indications

Hyperargininemia Leukemia, Myeloid, Acute Myelodysplastic Syndromes Neoplasms Neoplasms Small Cell Lung Carcinoma

ATC Classification

A16AB24
pegzilarginase
Level 1: ALIMENTARY TRACT AND METABOLISM
Level 2: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS

Data from ChEMBL 36 via Core Engine