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Compound Detail

CHEMBL4298037

RETIFANLIMAB
💊 Approved Drug
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💊 Approved Drug
No structure available

Basic Information

ChEMBL ID CHEMBL4298037
Name RETIFANLIMAB
Phase Approved
Structure Type SEQ
Therapeutic ✓ Yes

Known Names

AEX-1188 AEX1188 INCMGA-00012 INCMGA-0012 Incmga00012 MGA-012 Mga012 Retifanlimab Retifanlimab-dlwr Zynyz
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
10
Known Names
20
Indications
1
Mechanisms

Drug Information

Molecule Type Antibody
First Approval 2023
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Parenteral
USAN Stem -mab
USAN Year 2020

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Programmed cell death protein 1 antagonist ANTAGONIST Programmed cell death protein 1

Indications

Carcinoma, Merkel Cell Carcinoma, Squamous Cell Carcinoma, Squamous Cell Neoplasms Neoplasms Carcinoma, Non-Small-Cell Lung Breast Neoplasms Breast Neoplasms Breast Neoplasms Endometrial Neoplasms Esophageal Neoplasms Glioblastoma Head and Neck Neoplasms Liposarcoma Malignant Carcinoid Syndrome Neuroendocrine Tumors Pancreatic Neoplasms Paraganglioma Sarcoma Sarcoma

ATC Classification

L01FF10
retifanlimab
Level 1: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Level 2: ANTINEOPLASTIC AGENTS

Data from ChEMBL 36 via Core Engine