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Compound Detail

CHEMBL4298149

ARIMOCLOMOL CITRATE
💊 Approved Drug
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💊 Approved Drug
O=C(O)CC(O)(CC(=O)O)C(=O)O.[O-][n+]1cccc(/C(Cl)=N/OC[C@H](O)CN2CCCCC2)c1

Basic Information

ChEMBL ID CHEMBL4298149
Name ARIMOCLOMOL CITRATE
Phase Approved
Structure Type MOL
InChI Key XSENLDLUMVYRET-NIOGVPEESA-N
Therapeutic ✓ Yes
Parent Compound CHEMBL2107726
Active Moiety CHEMBL2107726

Known Names

Arimoclomol citrate Miplyffa Orphazyme a/s
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
3
Known Names
1
Indications
1
Mechanisms

Molecular Properties

313.8
MW (Da)
1.08
ALogP
5
HBA
1
HBD
72.0
PSA (Ų)
0.37
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
First Approval 2024
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Oral

Flags

First in Class
USAN Stem -clomol
USAN Year 2018

Extended Properties

Molecular Formula C20H28ClN3O10
MW 505.91
Aromatic Rings 1
Heavy Atoms 21
NP-Likeness -1.10

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Unknown - -

Indications

Niemann-Pick Disease, Type C

Data from ChEMBL 36 via Core Engine