Compound Detail
CHEMBL4298879
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4298879 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CRDYSYOERSZTHZ-UHFFFAOYSA-N |
2
Targets
6
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
106.0
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 6 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Carbonic anhydrase 1 CHEMBL261 | Ki | 5.07 | 5.07 | 8500.0 | 1 |
| Carbonic anhydrase 2 CHEMBL205 | Ki | 4.07 | 4.07 | 86000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Carbonic anhydrase 1 | Ki | = | 8500.0 | nM | 5.07 | Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped-flo... | 27283786 |
| Carbonic anhydrase 2 | Ki | = | 86000.0 | nM | 4.07 | Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flo... | 27283786 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27283786 | 10.1016/j.bmc.2016.05.029 | Unchecked | 4 |
| 27283786 | 10.1016/j.bmc.2016.05.029 | Carbonic anhydrase 2 | 1 |
| 27283786 | 10.1016/j.bmc.2016.05.029 | Carbonic anhydrase 1 | 1 |
Data from ChEMBL 36 via Core Engine