Compound Detail
CHEMBL431810
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Basic Information
| ChEMBL ID | CHEMBL431810 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DBUMZMQWHAFLDR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
378.4
MW (Da)
5.14
ALogP
5
HBA
1
HBD
63.8
PSA (Ų)
0.67
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin releasing factor receptor CHEMBL2111360 | Ki | 6.22 | 6.22 | 602.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin releasing factor receptor | Ki | = | 602.0 | nM | 6.22 | Binding affinity at Corticotropin releasing factor receptor of rat cortical homo... | 12482442 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12482442 | 10.1016/s0960-894x(02)00835-1 | Corticotropin releasing factor receptor | 1 |
Data from ChEMBL 36 via Core Engine