Compound Detail
CHEMBL431886
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL431886 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XFOMXNHDAXGOKI-YSMPRRRNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
398.9
MW (Da)
6.05
ALogP
5
HBA
0
HBD
52.3
PSA (Ų)
0.36
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin releasing factor receptor CHEMBL2111360 | Ki | 8.64 | 8.64 | 2.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin releasing factor receptor | Ki | = | 2.3 | nM | 8.64 | In vitro binding affinity to the CRF receptor in rat cortical homogenates | 12467631 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12467631 | 10.1016/s0960-894x(02)00833-8 | Corticotropin releasing factor receptor | 1 |
Data from ChEMBL 36 via Core Engine