Compound Detail
CHEMBL438108
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Basic Information
| ChEMBL ID | CHEMBL438108 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZHHVEXKQFHIESX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
282.4
MW (Da)
2.29
ALogP
4
HBA
1
HBD
50.2
PSA (Ų)
0.92
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.05 | 5.05 | 9000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 9000.0 | nM | 5.05 | Inhibition of fMLP-OMe-induced chemotaxis in human neutrophils | 17475488 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17475488 | 10.1016/j.bmcl.2007.04.036 | Unchecked | 3 |
| 17475488 | 10.1016/j.bmcl.2007.04.036 | fMet-Leu-Phe receptor | 1 |
Data from ChEMBL 36 via Core Engine