Compound Detail
CHEMBL438941
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Cc1cn(CC(=O)N(CCNC(=O)CCC(=O)O)CC(=O)NCCN(CC(=O)NCCN(CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CCCNC(=N)N)C(N)=O)C(=O)Cn2ccc(N)nc2=O)C(=O)Cn2cnc3c(=O)[nH]c(N)nc32)c(=O)[nH]c1=O
Basic Information
| ChEMBL ID | CHEMBL438941 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TYUSMTYOXAVKCE-WUFIBBRRSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
2960.2
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 7.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rev responsive element (RRE) RNA CHEMBL613297 | Kd | 7.77 | 7.77 | 17.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rev responsive element (RRE) RNA | Kd | = | 17.0 | nM | 7.77 | Dissociation constant of compound with Rev-responsive element (RRE) IIB RNA was ... | 11354369 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11354369 | 10.1016/s0960-894x(01)00169-x | Rev responsive element (RRE) RNA | 2 |
Data from ChEMBL 36 via Core Engine