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Compound Detail

CHEMBL439106

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C[C@H](O)[C@@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NNC(=O)CCCCCN2/C(=C/C=C/C=C/C=C/C3=[N+](CCCCCC(=O)NN[C@H](Cc4ccccc4)C(=O)N[C@H]4CSSC[C@H](C(=O)N[C@H](C(=O)O)[C@@H](C)O)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc5c[nH]c6ccccc56)NC(=O)[C@H](Cc5ccc(O)cc5)NC4=O)c4ccc5ccccc5c4C3(C)C)C(C)(C)c3c2ccc2ccccc32)CSSC[C@@H](C(=O)N[C@@H](C(=O)O)[C@H](C)O)NC1=O

Basic Information

ChEMBL ID CHEMBL439106
Phase Preclinical
Structure Type MOL
InChI Key OUUKJOSTOOGNGD-ACACWULTSA-O
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

2802.4
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C145H179N24O26S4+
MW 2802.44

Activity Summary

IC50 1 meas. best 8.96

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Somatostatin receptor
CHEMBL2096977
IC50 8.96 8.96 1.1 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
11985468 10.1021/jm010519l Somatostatin receptor 1

Data from ChEMBL 36 via Core Engine